15/11/2016
Equipe “Immunologie et immuno-intervention thérapeutique”, dirigée par S. Lacroix-Desmazes et S. Kaveri
Tackling Difficult Staphylococcus aureus Infections:
Antibodies Show the Way.
Bo Shopsin, Srini V. Kaveri, Jagadeesh Bayry
Abstract:
The recent spread of community-acquired methicillin-resistant Staphylococcus aureus (MRSA) has brought increasing concerns of heightened disease severity and persistence following invasive disease. In line with the need for new treatment paradigms, two recent reports have shown that antibody-based therapies can restrict acute S. aureus infection and persistence and improve pathological symptoms.
Keywords:
IVIG; Immunoglobulin; Panton-Valentine leukocidin; Thiomab; antibiotic; intravenous immunoglobulin; necrotizing pneumonia; phagocytes; rifalogue; α-hemolysin
Web Link: http://www.cell.com/cell-host-microbe/fulltext/S1931-3128(16)30444-9
Cell Host Microbe. 2016 Nov 9;20(5):555-557. doi: 10.1016/j.chom.2016.10.018.