Histology

Histology Platform

Join us on our histology platform and marvel at the beauty and diversity of the biological world

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PRESENTATION

Immerse yourself in a journey to the heart of the cell on our histology platform! Discover a world where biological tissues become works of art, thanks to our expertise and our cutting, embedding and staining techniques. Each sample is meticulously prepared to reveal its innermost secrets, offering an exploration of cellular structures and protein interactions. With our innovative multiplexing approach, you can explore multiple biological markers simultaneously, opening up new perspectives on the complexity of biology.

SERVICES

Our team is there to support you every step of the way, putting its expertise and know-how at your disposal to guarantee fast, efficient answers to all your questions.

  • Assistance and training in instrument use.
  • Support in setting up your experiments.
  • Management of complete workflows (inclusion/cuts/staining or multiplex marking/scanning).
  • Collaboration and development of new experimental protocols.
  • Technology watch: regular contact with our suppliers’ application engineers.

EQUIPMENTS

ASP300S Fully Enclosed Tissue Processor- LEICABiosystem

Service only

Automated dehydration system on fixed tissue. Up to 300 blocks per run.

!! Samples deposited on Wednesday before 4pm in 70% ethanol bath !!


HistoCore Arcadia Embedding Center- LEICABiosystem

Service and supply

Embedding on fixed and dehydrated tissue.

!! Thursdays !!

HistoCore LIGHTNING S – LEICABiosystem

UV laser engraving technology

Heat- and chemical-resistant printing

Compatible with various types and brands of blades


Microtome RM2145- LEICABiosystem

Service and supply

Cutting embedded blocks
Cutting thickness 0.25 to 60 µm


HistoCore AUTOCUT – LEICABiosystem

Srrvice and supply

Cutting embedded blocks


Cryostat CM3050 S – LEICABiosystem

Service and supply

Cutting blocks of OCT or dry
Cutting thickness 0.5 to 300 μm


HistoCore SPECTRA Workstation – LEICABiosystem

Service only

Automatic stainer + gluer. Up to 150 slides per run.

Available protocols: HE / HES / PicroSirius Red / Masson’s Trichrome /Dehydration

Link to LEICABiosystem-HistoCore SPECTRA


BOND RX Fully Automated Research Stainer – LEICABiosystem

Service and supply

Automat compatible with IHC, ISH, FISH, CTC, Multiplexing, RNAscope tests

Up to 30 slides in 7plex

Link to LEICABiosystem-BondRX


COMET – Lunaphore

Service and supply

HighMultiplex 40plex sequential immunofluorescence (seqIF™)

Stain area (9x9mm) – output image (ome-tiff) – tissue thickness (3-10µm) -2 slides – 40plex per run – TRITC / CY5 laser

Link to Lunaphore – COMET

Lunaphore Horizon Training – Video

FEES

Floriane Arbaretaz : Technical and operational manager – e-mail : floriane.arbaretaz@crc.jussieu.fr – Phone : 01 44 27 37 87

Julien Lavergne : cross-disciplinary project manager – e-mail: julien.lavergne@sorbonne-universite.fr – Phone : 01 44 27 37 44